\chapter{Introduction} \begin{definition}[Long Term Nonprocessor (LTNP)] Patient who will remain a long time in good health condition, even with a large viral load (cf. HIV). \end{definition} \begin{example}[Genotype: Qualitative or Quantitative?] \[ \text{SNP}: \begin{cases} \text{AA} \\ \text{AB} \\ \text{BB} \end{cases} \rightarrow \begin{pmatrix} 0 \\ 1 \\ 2 \end{pmatrix}, \] thus we might consider genotype either as a qualitative variable or quantitative variable. \end{example} When the variable are quantitative, we use regression, whereas for qualitative variables, we use an analysis of variance.