sequence-algorithms/content/chapters/part1/3.tex

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\chapter{Automata for motif search}
Let $M$ be a motif $M = $ ACAT.
\begin{figure}
\centering
\includegraphics{./figures/part1/motif_search_automaton.pdf}
\caption{Motif search automaton for $M = $ ACAT}
\end{figure}
The alphabet of motif is the same as the alphabet of the sequence.
The search automaton is complete.
If the there exists a letter $c$ in the sequence that is not
in the motif alphabet, we can make a virtual transition from
each state to the initial state whenever we encounter an unknown letter.
\begin{algorithm}
\caption{Search a motif in a sequence with an automaton}
\begin{algorithmic}[1]
\Function{SearchMotif}{$S$: Array($n$), $A$: $\langle S, s_{0}, T, \Sigma, f \rangle$, $P$: Array($m$)}
\Returns{A set of positions where the motif has been found}
\State $s \gets s_0$
\State $i \gets 0$
\State $pos \gets \{\}$
\While {$i < n$} % $\exists f(s, S[i])$ We assume $S$ and $P$ are formed on the same alphabet, so we could remove the second check, as $A$ is complete
\If {$s \in T$}
\State $pos \gets pos \cup \{ i - m \}$
\EndIf
\State $s \gets f(s, S[i])$
\State $i++$
\EndWhile
\State \Return $pos$
\EndFunction
\end{algorithmic}
\end{algorithm}
\begin{algorithm}
\caption{Check if the a motif automaton recognizes only the prefix of size $m-1$ of a motif $P$ of size $m$ }
\begin{algorithmic}[1]
\Function{SearchMotifLastPrefix}{$S$: Array($n$), $A$: $\langle S, s_{0}, T, \Sigma, f \rangle$, $P$: Array($m$)}
\Returns{A set of positions where the motif has been found}
\State $s \gets s_0$
\State $i \gets 0$
\State $T_{new} \gets \{\}$
\For {$s \in S$}
\For {$a \in \Sigma$}
\For {$t \in T$}
\If {$\exists f(s, a)$ and $f(s, a) = t$}
\State $T_{new} \gets T_{new} \cup s$
\EndIf
\EndFor
\EndFor
\EndFor
\While {$i < n$}
\If {$s \in T_{new}$}
\State \Return \True
\EndIf
\State $s \gets f(s, S[i])$
\State $i++$
\EndWhile
\State \Return \False
\EndFunction
\end{algorithmic}
\end{algorithm}
\begin{algorithm}
\caption{Check if the a motif automaton recognizes only the prefix of size $m-1$ of a motif $P$ of size $m$, knowing the sequence of the motif}
\begin{algorithmic}[1]
\Function{SearchMotifLastPrefix}{$S$: Array($n$), $A$: $\langle S, s_{0}, T, \Sigma, f \rangle$, $P$: Array($m$)}
\Returns{A set of positions where the motif has been found}
\State $s \gets s_0$
\State $i \gets 0$
\While {$i < n$ and $f(s, P[m-1]) \notin T$}
\State $s \gets f(s, S[i])$
\State $i++$
\EndWhile
\If{$f(s, P[m-1]) \in T$}
\State \Return \True
\Else
\State \Return \False
\EndIf
\EndFunction
\end{algorithmic}
\end{algorithm}